ABSTRACT
Primary leiomyoma of the chest wall is extremely rare. A 13-month-old boy presented to outpatient clinic of the department of pediatrics with a soft, movable, and palpable mass in the right supraclavicular area. Neck computed tomography revealed a 2.5-cm-sized soft tissue mass in the right anterior supraclavicular area. The mass was completely resected, and histopathological examination showed a localized primary leiomyoma with cystic change. The patient was followed up and has been disease-free for more than 11 months since surgery. To the best of our knowledge, 13 cases of leiomyoma of the chest wall have been reported to date, but this is the second case of primary leiomyoma of the chest wall in a pediatric patient. This report describes the clinical course of this case and presents a review of relevant literature.
Subject(s)
Humans , Infant , Male , Ambulatory Care Facilities , Leiomyoma , Neck , Pediatrics , Smooth Muscle Tumor , Thoracic Wall , ThoraxABSTRACT
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete aldosterone or androgen. Estrogen-secreting adrenocortical carcinomas are extremely rare, irrespective of the secretion status of other adrenocortical hormones. Here, we report the case of a 53-year-old man with a cortisol and estrogen-secreting adrenocortical carcinoma. The patient presented with gynecomastia and abdominal discomfort. Radiological assessment revealed a tumor measuring 21×15.3×12 cm localized to the retroperitoneum. A hormonal evaluation revealed increased levels of estradiol, dehydroepiandrosterone sulfate, and cortisol. The patient underwent a right adrenalectomy, and the pathological examination revealed an adrenocortical carcinoma with a Weiss' score of 6. After surgery, he was treated with adjuvant radiotherapy. Twenty-one months after treatment, the patient remains alive with no evidence of recurrence.
Subject(s)
Humans , Male , Middle Aged , Adrenal Gland Neoplasms , Adrenalectomy , Adrenocortical Carcinoma , Aldosterone , Dehydroepiandrosterone Sulfate , Estradiol , Gynecomastia , Hydrocortisone , Incidence , Radiotherapy, Adjuvant , RecurrenceABSTRACT
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete aldosterone or androgen. Estrogen-secreting adrenocortical carcinomas are extremely rare, irrespective of the secretion status of other adrenocortical hormones. Here, we report the case of a 53-year-old man with a cortisol and estrogen-secreting adrenocortical carcinoma. The patient presented with gynecomastia and abdominal discomfort. Radiological assessment revealed a tumor measuring 21×15.3×12 cm localized to the retroperitoneum. A hormonal evaluation revealed increased levels of estradiol, dehydroepiandrosterone sulfate, and cortisol. The patient underwent a right adrenalectomy, and the pathological examination revealed an adrenocortical carcinoma with a Weiss' score of 6. After surgery, he was treated with adjuvant radiotherapy. Twenty-one months after treatment, the patient remains alive with no evidence of recurrence.